I have been doing a great deal of research on neurotransmitters and their effect on the brain, body and every day life. Being a personal trainer, I routinely field resistance training questions, nutrition questions and cardiovascular concerns. What I have been noting is still a trend in inquiries around motivation, the brain and even techniques to deal with depression. The traditional approach in the past has been to speak with your family physician or a specialist so they can run a few tests and prescribe that medication is supposed to help you deal with the symptoms you may be experiencing. These can range from sadness, laziness, lack of motivation, lethargic, lack of sleep, irritable, etc.
Some common medications are Wellbutrin, Paxil, Elavil, Remeron and the like. I will discuss in greater detail why these may not be meeting your expectations and why some natural amino acids when combined produce astonishing results that not only elevate your serotonin and dopamine levels but keep them high when you cease taking the amino acids. Please note that I have a few Medical Doctors as former and current clients and I am by no means recommending you stop your medication, but I am giving you an alternative to take in conjunction with your prescribed medication or entirely on their own.
To get a better understanding on how prescription medications and amino acids work, you must look at the two primary neurotransmitters and they are serotonin and dopamine. There are others that play a role in your vitality but these two are the primary components that need to be functioning at optimal capacity. It has been documented that 93% of patients on anti-depressants show no progress or change at all when on the medication. The main reason for this is that serotonin and dopamine are largely found in the gut (near the kidney) and the around the brain. When on most prescription medications, the serotonin and dopamine stay in the synapses outside the kidney and brain because the medications are not constructed to pass through the OCT2 transporters (or gates) that would give all the benefit to the brain and kidney. Therefore you have an influx and abundance of serotonin and dopamine on the outside which are not fulfilling their intended purpose of increasing serotonin and dopamine levels within the brain cells.
You now may be asking the million dollar question of how can you penetrate the gates of the brain and have the serotonin and dopamine reach the kidney and brain as both are related. The answer is through a regimen that includes the amino acids tyrosine (which increases dopamine) and 5-HTP (which increases serotonin) with a B6 vitamin. These amino acids have been shown in studies by Dr. Daniel Kalish ( http://www.drkalish.com/index2.html ) to have the ability to open the OCT2 transporters and allow the serotonin and dopamine to flood the brain and kidneys. Taking 1000mg of Tyrosine, 100mg of 5-HTP (10 to 1 ratio) and a B 6 vitamin three times a day have yielded very high levels of serotonin and dopamine inside the cells and the results were very satisfied clients / patients who have never felt better. This includes more energy, better sleep patterns, reduced appetite, and the list goes on. The reason for this dosage ratio is that serotonin and dopamine are antagonistic meaning as one increases, the other one decreases so you have to balance them out and ensure both go up or you will not have the desired effect. Dr. Kalish describes this in detail on his site and I strongly encourage you to visit his site. This is revolutionary information that has changed the lives of thousands of people but the problem is most people do not even know about it. As discussed, you can take these amino acids on their own or in conjuction with your prescription medication. It is completely up to you. I do not recommend stopping “cold turkey” from your medication and please speak with your doctor should you be encouraged to try this approach. I highly recommend it and let me know how you feel after a few days, weeks and months. I think you will be pleasantly surprised. Thanks and have an excellent day.